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نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 67053
شماره مدرک : ‭پ۵۳۵۳۲‬
شماره راهنما : ‭ع۶۷۱۸‬
سر شناسه : ایزد پناهی، نوشین
عنوان اصلي : بررسی میزان پاسخ به درمان جراحی در بیماران مبتلا به تومور تروفوبلاستیک حاملگی‭(GTN)‬
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /نوشین ایزد پناهی
نام ساير پديدآوران : ؛استاد راهنما: ملیحه حسن زاده، فاطمه همایی
نام ساير پديدآوران : ؛استاد مشاور: زهره یوسفی، منور افضل آقایی
عنوان ديگر : عنوان به انگلیسی‭Evaluation of response rate to surgery of gestational trophoblastic neoplasia (GTN) :‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۲‬، دانشکده پزشکی
صفحه شمار : ‮‭[۶۵]‬ ص.‬: نمودار
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭omid hospital from March 2000 to March 2010 were studies retrospectively. Surgical procedures included hysterectomy, hysterotomy, lung resection and craniotomy. Indications for adjuvant surgery were resistance to chemotherapy and bleeding. Therapeutic response was defined as complete with normalization of human chorionic gonadotropin (hCG) concentration, partial response with a decrease of more than 50 , and no response with a decrease of 50 or less in 6 weeks after surgery. Results: patient with GTD who underwent surgical procedures accounted for 31 cases. No deaths were recorded. Survival rate in mean of follow up (12 month) were 100 . Mean (SD: 10.55) age was 36 years. Surgical procedures included hysterectomy in 21 patients (67.7 ), hysterotomy in 6 patients (19.4 ), lung resection in 3 patients (9.7 ) and craniotomy in 1 patient (3.2 ). 22 patients (71 ) showed complete response and 9 patients (29 ) showed partial response. Conclusion: surgical procedures play an important role in management of GTD. Antecedent non molar pregnancy, tumor stage, WHO scoring are clinical predictors of response to surgery. Key words: gestational trophoblastic disease, surgery, Therapy &Introduction: gestational trophoblastic disease (GTD) is a group of rare tumors ranging from the benign hydatidiform mole to the malignant choriocarcinoma. Majority of patients are cured with chemotherapy treatment but some of them become chemotherapy resistant and need to salvage surgical procedures. The role of surgery in treatment of patients is not clear. This study performed to evaluate the response rate to surgery of gestational trophoblastic neoplasia. Methods: All files related to patient with GTD who underwent surgical procedures during treatment in Medical Gynecologic Oncology Research Center, ghaem‬
 
 
 
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