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رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66957
شماره مدرک : ‭پ۵۳۴۶۶‬
شماره راهنما : ‭ت۲۸۵۹‬
سر شناسه : بیرقی طوسی، مهران
عنوان اصلي : بررسی اثر بخشی لوتیراستام در کنترل تشنج در کودکان مبتلا به صرع مقاوم به درمان
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /مهران بیرقی طوسی
نام ساير پديدآوران : ؛استاد راهنما: جواد آخوندیان، فرح اشرف زاده
عنوان ديگر : عنوان به انگلیسی‭The effect of levetiracetam on intractable on pediatric seizures:‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۱‬، دانشکده پزشکی
صفحه شمار : ‮‭[۶۸]‬ ص.‬: جدول، نمودار
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭clonic (GTC) seizures were treated; but 46.8 of myoclonic and 42.97 of focal seizures were exaggerated; but there was not statistically difference (P=0.38). All patients with GTC had satisfaction of the drug; but 20 to 30 of patients with focal and 30 to 45 of patients with myoclonic seizures were satisfied (not statistically different). Three patients had severed anorexia and one had somnolence with the drug.Conclusion: The percent of reduction of seizures did not statistically changed with the use of levetiracetam (Biolepra); but it seems to be better for GTC seizures and older children.-on therapy is assessed.Methods: In this clinical trial, all children age 2 to 16 years with intractable epilepsy that came to our center, were evaluated. Patients were checked 1 month for mean number of seizures, and then we add on oral levetiracetam (Biolepra) with the dose of 10mg/Kg/day to their previous regimen. The dose of levetiracetam was elevated 10mg/Kg/day weekly up to optimal dose of 50mg/Kg/day and then we followed the dose for 4 weeks (total duration was 8 weeks). Every week we were cheeked the number of seizures, probable side effects, and satisfactory rate of parents from the drug. Results: Thirty two patients were included. Fourteen cases (43.8 ) were male and 18 cases (56.2 ) were female. In the end of study, all children with generalized tonic-Background: About 15 of children with epilepsy are intractable; so we need new methods and therapies. In this study, the effect of levetiracetam on intractable epilepsy in the form of add‬
 
 
 
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