خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66946
شماره مدرک : ‭پ۵۳۴۴۷‬
شماره راهنما : ‭آ۳۹۴‬
سر شناسه : احمدی، مریم
عنوان اصلي : اثر عصاره هیدروالکلی گیاه اشنان‭(Seidlitzia rosmarinus)‬ در درمان لیشمانیوز پوستی تجربی در مدل موشی
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /مریم احمدی
نام ساير پديدآوران : ؛استاد راهنما: عبدالمجید فتی
نام ساير پديدآوران : ؛استاد مشاور: علی خامسی پور، حسن رخشنده
عنوان ديگر : عنوان به انگلیسی‭The efficacy of Hydro alcoholic extrat of Seidlitzia rosmarinus on treatment of experimental zoonotic cutaneouse leishmaniasis in murine model :‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۱‬، دانشکده پزشکی
صفحه شمار : ‮‭[۹۴]‬ ص.‬: مصور
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭alcoholic extract of S.rosmarinuse prepared by Soxhelt apparatus. The surface area of lesion were measured before and 8 weeks after treatment by Kulis Vernier. Direct Geimsa stained smear prepared 2 and4 weeks after treatment.Results: The mean of lesion size of the mice that received 5and 10 S. rosmarinus extracts showed statistically significant increase of ulcer size compared to the mean of the lesion size of the mice in control group (P>0.001). Conclusion: When the mice infected with Rural Cutaneous Leishmaniasis Leishmania (L) major were not treated, they develop Visceral Leishmaniasis. When lesion size of the Cutaneous Leishmaniasis widened, the animal would die. Survival function of the mice that received 15 S. rosmarinus extracts showed statistically significant difference compared to mice in control group (P>0.001).Keywords: Leishmania (L) major, Cutaneous Leishmaniasis, Seidlitzia rosmarinus.-Background: Leishmaniasis is one of the most important infectious diseases in the world. There are wide differences in the clinical features of Leishmaniasis. Efforts have been made since more than a century ago to control and treat the disease, but appropriate vaccines, drugs and pesticides have not yet been prepared. While in these conditions, alternative medicines and herbal medicines were approved by WHO.The purpose of this study was to examine the effect of hydro alcoholic extract of Seidlitzia rosmarinus on cutaneous leishmaniasis in Balb/c Mice.Method: The Balb/c mice were infected with 4.8106 viable promastigotes of leishmania (L) major [MRHO/75/IR]. Soon after the ulcer started to appear in the early stage, one dose of the herbal medicine with 5, 10 and 15 concentration on ocerin base was used to treat the ulcer. The hydro‬
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)