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رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66927
شماره مدرک : ‭پ۵۳۴۳۸‬
شماره راهنما : ‭ع۶۸۷۷‬
سر شناسه : فتوحی، مرضیه
عنوان اصلي : بررسی مقایسه ای اثرات سینووکس و بتافرون بر روی میزان خستگی در بیماران مبتلا به مالتیپل اسکلورزیس مراجعه کننده به درمانگاه‭MS‬ بیمارستان قائم (عج‭(‬
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /مرضیه فتوحی
نام ساير پديدآوران : ؛استاد راهنما: کریم نیکخواه، علی شعیبی
نام ساير پديدآوران : ؛استاد مشاور: مطهره پارسا
عنوان ديگر : عنوان به انگلیسی‭The Comparitive study of fatigue in patients suffered from multiple sclerosis after 6 months treatment with cinnovex and betaferon, referred to ghaem hospital :‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۱‬، دانشکده پزشکی
صفحه شمار : ‮‭[۱۳۴]‬ ص.‬: مصور
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭Intoduction: Multiple sclerosis is (MS) one of the central nervous system disorders that usually affect young females. One of the common symptoms of this disease is fatigue that it greatly interfers with the patients quality of life. Because of the fact that interferons are known as protective agents against MS symptom, in this study we aimed to evaluate the effectiveness of these agents in fatigue of these patients and compare the potncy of two commonly used interferone (Cinnovex and Betaferon) on fatigue of MS patients.Methods: In this cohort study 62 MS patient who received betaferon or cinnovex as their disease modifying treatment were evaluated. Fatigue was evaluated according to Fatigue Severity Scale (FSS). After 6 months treatment with Cinnovex or Betaferon, FSS scores were compared between two therapeutic groups. P value lesser than 0.05 was considered significant.Result:The study evaluated 62 patients(32patients were treated with cinnovex and 30 patient with betaferon)the mean average sex was 78.5 in female and 24.2 in males.the mean average in age was 29.24‬▒‭6.02.Fatigue severity scale(FSS) at first was 3.88‬▒‭0.12 in betaferon group and 3.82‬▒‭o.11 in cinnovex group.after 6months,FSS was 2.9‬▒‭0.11 in betaferon and 2.99‬▒‭0.09 in cinnovex group.the mean average in EDSS at first was 3.25‬▒‭0.7 in betaferon and 2.93‬▒‭0.56 in cinnovex group.after 6 month EDSS was 2.5‬▒‭0.56 in betaferon and 2.3‬▒‭0.59 in cinnovex group that show decreasing in EDSS and FSS during 6 month treatment. Conclusion:it seems that both cinnovex and betaferon are equally effective in treatment of fatigue in MS patient with approximately similar side effects.the lower price and easier accessibility of the cinnovex in iran,this study sugguests that cinnovex might be a good choice for the treatment of MS patient.Keywords:multiple sclerosis,betaferon,cinnovex,fatigue,fatigue severity scale ,Expanded Disability Status Scale‬
 
 
 
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