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رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66917
شماره مدرک : ‭پ۵۳۴۲۶‬
شماره راهنما : ‭ع۶۷۴۴‬
سر شناسه : بخشنده، طاهره
عنوان اصلي : بررسی نتایج درمانی رژیم‭MTX‬ عضلانی هفتگی در درمان بیماران به تومورهای ترفوبلاستیک حاملگی‭(GTN)‬ کم خطر
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /طاهره بخشنده
نام ساير پديدآوران : ؛استاد راهنما: ملیحه حسن زاده، فاطمه همایی شاندیز
نام ساير پديدآوران : ؛استاد مشاور: محمد تقی شاکری
عنوان ديگر : عنوان به انگلیسی‭Evaluation of weekly intramuscular methotrexate in the treatment of low-risk gestational trophoblastic neoplasia :‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۰‬، دانشکده پزشکی
صفحه شمار : ‮‭[۸۳]‬ ص.‬: :مصور
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭risk patients with score 6. Escalation of MTX dose is effective in improving treatment results. -GTN, it is not effective in low-up.Conclusion:Although weekly intramuscular regimen is an efficient treatment for LR-52 yr) . Complete remission was achieved in 74 of 117 patients (63.2 ) with primary dose of methotrexate( 50mg/m2) , with dose escalation to 75mg/m2 Complete remission was achieved in 87 patients ( 74.3 ). 22 of 30 patients had a CR with actinomycin. 8 patients achieved CR with combination chemotherapy. There were significant statistical relationship between remission and WHO score, Figo stage, pre treatment BHCG level and antecedent pregnancy(p<0.05) .No recurrence or death reported during 1 yr follow-treatment BHCG level, duration from antecedent pregnancy ,etc were collected , scoring and disease staging according to WHO and FIGO systems were performed based on collected datas.Then statistical analysis was performed on datas using version 11.5 SPSS software.Results: The mean age of our patients was 27.9 years( 15-risk GTN in Quaem and Omid hospitals patients were treated weekly with 50mg/m2 methotexate and BHCG level were measured weekly until 3 consecutive negative level( defined as Complete remission (CR) ) .Patients datas such as age, antecedent pregnancy , pre-risk GTN.Method: 117 patients with low-line treatment of low-metastatic according to FIGO staging system. The aim of this research is evaluating results of weekly intramuscular methotrexate as first-risk(score>=7) group according to WHO scoring system and into metastatic and non-risk ( score <7) and high-site trophoblastic tumour. Patients with GTN are classified to Low-threatening malignancies that arise from human placental trophoblastic villi and consist of the premalignant disorders of complete and partial hydatidiform mole, and the malignant disorders of invasive mole, choriocarcinoma, and the rare placental-Background: Gestational trophoblastic tumors are rare and potentially life‬
موضوع : ‭Musculoskeletal System‬
 
 
 
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