خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66782
شماره مدرک : ‭پ۵۲۳۴۴‬
شماره راهنما : ‭ع۶۷۷۴‬
سر شناسه : مظلوم خراسانی، جواد
عنوان اصلي : نقش مصرف فولات بر سطح سرمی هموسیستئین و ویتامین‭B12‬ در بیماران دیابتی تحت درمان با متفورمین
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /جواد مظلوم خراسانی
نام ساير پديدآوران : ؛استاد راهنما: زهره موسوی
نام ساير پديدآوران : ؛استاد مشاور: محمد تقی شاکری
عنوان ديگر : عنوان به انگلیسی‭The role of using Folate on Homocysteine and vitamin B12 serum level in diabetics who treated with Metformin :‬
وضعيت نشر : دانشگاه علوم پزشکی مشهد، ‭۱۳۹۱‬، دانشکده پزشکی
صفحه شمار : ‮‭[۵۵]‬ ص.‬: نمودار
يادداشت : چکیده فارسی، چکیده انگلیسی
يادداشت : چاپی
خلاصه يا چکيده : ‭platlete. But we have reduction in hemoglobin level in this group form 14.94 to 14.72 . (P = 0.036) Conclusion: Complementary treatment with folic acid in patients with type diabetes that are on metformin can prevent increasing Homocysteine levels. Also this treatment can increase B12 levels. Therfore it is useful to add folic acid in these patients. Key words: Folic acid, Vitamin B12, Diabetes, Metformin, Homocysteine & Platlete. In placebo group homocysteine increase from 14.4 to 17.1 (P= 0.007) and Vit B12 decrease from 211.8 to 187.04 ( P = 0.063 ) . Also in this group there was no significant change in WBC, MCV & 0.6)and average of Vit B12 levels increase from 244.87 to285.54 (P = 0.025) . In this group we have reduction in WBC from 7.27 to6.62 (P=0.005) and increase in MCV from 86.64 to 88.81 (P= 0.002) . Treatment with folic acid didnt have significant effect on, Hemoglobin, - Biochemistary at the base and after treatment levels of Homocysteine, Vit B12 and CBC were checked again and drug effect were examined. Results: In folic acid group Homocysteine decrease from 12.8 to12.4 (P = & Placebo. 24patients receaved 1mg folic acid per day for three monthes and 21 patients as a witness received placebo. This patiens inter in a study if had GFR> 60 . We checked CBC, Vit B12 , Homocysteine &Introduction: Diabetes have so many complications. Metformin is widely used in diabetics that have complications like reduction of VitB12 and increasing the homocysteine. High levels of homocysteine can be a risk factor for cardiovascular disorders. Complementary therapy with folic acid can prevent homocysteine increment. Also this medicine can increase the vitB12. Method: 45 person selected from patients with type diabetes that were on metformin and devided into two groups : Folic acid‬
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)