خط مشی دسترسیدرباره ما
ثبت نامثبت نام
راهنماراهنما
فارسی
ورودورود
صفحه اصلیصفحه اصلی
جستجوی مدارک
تمام متن
منابع دیجیتالی
رکورد قبلیرکورد بعدی
نوع مدرک : TF
زبان مدرک : فارسی
شماره رکورد : 66535
شماره مدرک : ‭پ۵۲۱۹۲‬
شماره راهنما : ‭ت۲۵۹۱‬
سر شناسه : سلوتی، سوزان
عنوان اصلي : بررسی اثر بخشی افزودن اندانسترون در علائم منفی اسکیزوفرنی
نام عام مواد : [پایان‌نامه]
نام نخستين پديدآور : /سوزان سلوتی
نام ساير پديدآوران : ؛استاد راهنما: علی آخوند پور منطقی
نام ساير پديدآوران : ؛استاد مشاور: محمد رضا فیاضی بردبار، شاهین آخوند زاده ، سعید اخلاقی
وضعيت نشر : دانشگاه علوم پزشکی مشهد : دانشکده پزشکی، ‭۱۳۹۱‬
صفحه شمار : ‮‭[۶۵]‬ ص.‬:مصور
يادداشت : تاریخ دفاع :‭ ۱۳۹۱/۳/۱۸ ‬، نمره پایان نامه :‭ ۱۹/۶۷ ‬، چکیده فارسی ، چکیده انگلیسی ، عنوان به انگلیسی‭The efficacy of ondansetron augmentation in negative sign if schizophrenia :‬
يادداشت : چاپی
خلاصه يا چکيده : ‭R) in subscale verbal (comprehension) and performance (object assembly) were the significant improvement made in ondansetron group.Any difference among results of the study were not found among men and wemen after received ondansetron.Depressive symptoms of patients were not significant difference after trial. (P=0.557)Conclusion:Ondansetron as an adjunctive therapy with rispenden can improve negative symptoms specially in social withdrawal (N4) and affective blunting (N1) and also verbal and performance abilities in Schizophrenic patients can improve with ondansetron.Key words: Schizophrenia, Ondansetron, Negative sign-squar, Linear regression and Fisher's exact test.Results: in patients that received ondansetron, after 8 weeks there were significant improvement in negative symptoms. (P >0.001).Among the negative symptoms, social withdrawal (N4), affective and emotional withdrawal (N1), affective blunting (N1) were the most marked improvement. Lake of spontaneous speech and verbal fluency (N6) were not different between two groups.Wechsler adult intelligence scale (WAIS-test, wilcoxan test, Chi-test , paired sample t-R and HRSD in the beginning and in the end of the study.The data were analyzed by SPSS Ver.15 with independent sample t- diagnosed schizophrenia were randomly divided into two groups. All patients had received risperidon for two months, and subsequently received either placebo (N=20) or ondansetron 8mgd (N=18) for the period of 8 weeks. All patients were assessed by PANSS, WAIS-IV-blind randomized study Conducted from 19 Dec 2011 to 18 Mar 2012, 38 chronic DSM-Background: Negative symptoms are the most important symptoms of Schizophrenia as they can Predict functional outcome of patients.Serotoninergic receptors play an important role in pathogenesis of Schizophrenia. In this study we evaluated augmentation of ondansetron (5HT3 antagonist) with risperidon in negative symptoms of Schizophrenia.Methods and matherials: During double‬
 
 
 
(در صورت عدم وضوح تصویر اینجا را کلیک نمایید)